Product ID:O-TOLIDINE DIHYDROCHLORIDE
MSDS Date:06/30/1992
FSC:6810
NIIN:00N047656
MSDS Number: BVHSK

FISHER SCIENTIFIC, CHEMICAL DIV.

1 REAGENT LANE
FAIR LAWN, NJ 07410
US

Emergency Phone: 201-796-7100/800-424-9300(CHEMTREC)

Info Phone: 201-796-7100 OR 201-796-7523

Cage: 1B464

FISHER SCIENTIFIC CO. CHEMICAL MFG DIV

FAIRLAWN, NJ 07410-2802 US

Telephone: 201-796-7100

Cage: 1B464

HAVE BEEN REPORTED. NEOPLASMS OF SKIN, PREPUTIAL

RTECS: 9999999ZZ

INTESTINE, MAMMARY GLAND, LUNG, MESOTHELIUM, BRAIN &

RTECS: 9999999ZZ

CLITORIAL GLANDS & ALVEOLAR EPITHELIUM WERE OBSERVED

RTECS: 9999999ZZ

CLEAR EVID OF CARCIN ACTIVITY IN MALE & FEMALE RATS

RTECS: 9999999ZZ

SALINE, OCCAS LIFTING UPPER & LOWER LIDS,

RTECS: 9999999ZZ

TREAT SYMPTOMATICALLY &

RTECS: 9999999ZZ

NO

RTECS: 9999999ZZ

EFFICIENCY PARTICULATE FILTER; ANY TYPE 'C'

RTECS: 9999999ZZ

OR CONTINUOUS FLOW-MODE; ANY SELF-CONTAINED BREATHING

RTECS: 9999999ZZ

THERE IS ANY POSSIBILITY THAT EMPLOYEE'S

RTECS: 9999999ZZ

EMPLOYER SHLD PROVIDE EMERG EYEWASH & DELUGE SHOWER

RTECS: 9999999ZZ

BENZIDINE, 3,3'-DIMETHYL-, DIHYDROCHLORIDE; (O-TOLIDINE

CAS: 612-82-8

RTECS: DD1226000

Fraction By Weight: 100%

OSHA PEL N/K

ACGIH TLV: N/K

LD50 LC50 Mixture:LD50:(ORAL,RAT) 566 MG/KG.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE:INHAL:MAY CAUSE COUGH, DFCLTY
BRTHG, DIZZ & HDCH. SKIN:MAY BE ABSORBED THRU SKIN & CAUSE IRRIT.
EYE:MAY CAUSE IRRIT W/POSS BURNS. INGEST:MAY CAUSE NAUS.
CHRONIC:SKIN:SOME BENZIDINE CMPDS MAY CAU SE DERM DUE TO
IRRIT/SENSIT. EYE:RPTD/PRLNG CONT W/IRRITS MAY RSLT IN CONJ.
INGEST:RATS EXPOS TO 300- (EFTS OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT
Effects of Overexposure:HLTH HAZ:7,500 PPM IN DRINKING WATER FOR 14
DAYS TO 13 WKS EXHIBITED ATAXIA & DEATH. NEPHROPATHY, INCR
VACUOLIZATION & NECROSIS OF ADRENAL CORTEX CELLS, HEPATOCELLULAR
NECROSIS W/DMG & ACCUM OF BROWN PIGMENT IN HEPATOCELLULAR
SINUSOIDAL LINING CELLS, ATROPHY OF BONE MARROW, FACAL ACINAR CELL
DEGENERATION IN (SUPP DATA)
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

First Aid:INHAL:REMOVE FROM EXPOS AREA TO FRESH AIR IMMED. IF BRTHG HAS
STOPPED, PERFORM ARTF RESP. KEEP PERS WARM & AT REST. TREAT
SYMPTOMATICALLY & SUPPORTIVELY. GET MED ATTN IMMED. SKIN:REMOVE
CONTAM CLTHG & SHOES IMMED. WASH AFFECTED AREA W/SOAPOR MILD
DETERGENT & LG AMTS OF WATER UNTIL NO EVID OF CHEM REMAINS (APPROX
15-20 MINS). GET MED ATTN IMMED. EYE:WASH IMMED W/LG AMTS OF
WATER/NORMAL (ING 6)

Extinguishing Media:DRY CHEMICAL, CARBON DIOXIDE, WATER SPRAY OR
REGULAR FOAM. FOR LARGER FIRES, USE WATER SPRAY, FOG OR REGULAR
FOAM.
Fire Fighting Procedures:USE NIOSH/MSHA APPRVD SCBA & FULL PROT EQUIP .
MOVE CNTNR FROM FIRE AREA IF YOU CAN DO IT W/OUT RISK. DO NOT
SCATTER SPILLED MATL W/HIGH-PRESS (SUPP DATA)
Unusual Fire/Explosion Hazard:SLIGHT FIRE & HAZARD WHEN EXPOSED TO HEAT
OR FLAME. DUST-AIR MIXTURES MAY IGNITE OR EXPLODE.

Spill Release Procedures:OCCUPATIONAL SPILL:SWEEP UP & PLACE IN
SUITABLE CLEAN, DRY CONTAINER FOR RECLAMATION OR LATER DISPOSAL. DO
NOT FLUSH SPILLED MATERIAL INTO SEWER. KEEP UNNECESSARY PEOPLE
AWAY.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:STORE AWAY FROM INCOMPATIBLE
SUBSTANCES. STORE IN A TIGHTLY CLOSED CONTAINER.
Other Precautions:NONE SPECIFIED BY MANUFACTURER.

Respiratory Protection:SPECIFIC RESP SELECTED MUST BE NIOSH/MSHA
APPRVD:ANY DUST & MIST RESP; ANY AIR-PURIFYING RESP
W/HIGH-EFFICIENCY PARTICULATE FILTER; ANY POWERED AIR-PURIFYING
RESP W/DUST & MIST FILTER; ANY POWERED AIR -PURIFYING RESP W/HIGH-
(ING 9)
Ventilation:PROVIDE LOCAL EXHAUST VENTILATION. VENTILATION EQUIPMENT
MUST BE EXPLOSION PROOF.
Protective Gloves:IMPERVIOUS GLOVES .
Eye Protection:ANSI APPROVD CHEM WORKER GOGGLES .
Other Protective Equipment:EMPLOYEE MUST WEAR APPROP PROT (IMPERVIOUS)
CLTHG & EQUIP TO PVNT RPTD/PRLNG SKIN CONT W/THIS SUBSTANCE. WHERE
(ING 11)
Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER.
Supplemental Safety and Health
FIRE FIGHT PROC:WATER STREAMS. DIKE FIRE-CONTROL WATER FOR LATER DISP.
USE AGENTS SUITABLE FOR TYPE OF SURROUND FIRE. AVOID BRTHG HAZ
VAPS, KEEP UPWIND. EFTS OF OVEREXP:PANCREAS, VARYING DEGREES OF LY
MPHOCYTIC ATROPHY OF MANDIBULAR & MESENTERIC LYMPH NODES, SPLEEN &
THYMUS & INCR OF IMMATURE SPERM IN SOME MALES (ING 2)

HCC:N1
Melt/Freeze Pt:M.P/F.P Text:>644F,>340C
Vapor Pres:NEGLIGIBLE
Spec Gravity:>1
Solubility in Water:SLIGHTLY SOLUBLE
Appearance and Odor:WHITE TO YELLOW OR CREAM CRYSTALLINE POWDER.

Stability Indicator/Materials to Avoid:YES
OXIDIZERS (STRONG): FIRE & EXPLOSION HAZARD.
Stability Condition to Avoid:MAY BURN BUT DOES NOT IGNITE READILY.
AVOID CONTACT W/STRONG OXIDIZERS, EXCESSIVE HEAT, SPARKS OR OPEN
FLAME.
Hazardous Decomposition Products:THERMAL DECOMPOSITION PRODUCTS MAY
INCLUDE TOXIC OXIDES OF NITROGEN & CARBON & TOXIC & CORROSIVE FUMES
OF CHLORIDES.

Waste Disposal Methods:OBSERVE ALL FEDERAL, STATE & LOCAL REGULATIONS
WHEN DISPOSING OF THIS SUBSTANCE. FOR ASSISTANCE, CONTACT THE
DISTRICT DIRECTOR OF THE EPA.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.